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In addition, due to the inability to effectively detoxify CN, a deficiency of such amino acids has also been postulated to reduce a key antioxidant, glutathione, thereby hindering responses to the cyanide exposure-related oxidative stress, however, direct evidence of this mechanism has been scarce 12,13

Thalidomide use for complicated central nervous system tuberculosis in children: insights from an observational cohort

The compounds don't compete for binding sites, don't share metabolic pathways during clearance, and don't modulate the same downstream signaling cascades

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doi: 10.1016/j.micpath.2007.09.002 37 YagiK